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GPI-1485

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Purity:99.78%

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COA HNMR HPLC

GPI-1485

Catalog No. T9820Cas No. 186268-78-0

GPI-1485 (GM1485) (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.

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Pack Size	Price	Availability
1 mg	$67	In Stock
5 mg	$163	In Stock
10 mg	$247	In Stock
25 mg	$455	In Stock
50 mg	$672	In Stock
100 mg	$956	In Stock
1 mL x 10 mM (in DMSO)	$178	In Stock

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Product Introduction

Bioactivity

Description	GPI-1485 (GM1485) (GM1485) is a nonimmunosuppressive immunophilin ligand, promoting neurofunctional improvement and neural regeneration following stroke.
In vitro	GPI-1485 induced cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF) [1].
In vivo	GPI-1485 (5 mg/kg; intraperitoneal injection; 6-week period of daily) improved long-term neurological recovery in rats
Alias	GM1485

Chemical Properties

Molecular Weight	241.28
Formula	C12H19NO4
Cas No.	186268-78-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 95 mg/mL (393.73 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1446 mL	20.7228 mL	41.4456 mL	207.2281 mL
5 mM	0.8289 mL	4.1446 mL	8.2891 mL	41.4456 mL
10 mM	0.4145 mL	2.0723 mL	4.1446 mL	20.7228 mL
20 mM	0.2072 mL	1.0361 mL	2.0723 mL	10.3614 mL
50 mM	0.0829 mL	0.4145 mL	0.8289 mL	4.1446 mL
100 mM	0.0414 mL	0.2072 mL	0.4145 mL	2.0723 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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