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Hamaudol
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Catalog No. TN1723Cas No. 735-46-6
Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM.
Hamaudol
😃Good
Purity: 99.62%
Catalog No. TN1723Cas No. 735-46-6
Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $93 | In Stock | |
| 5 mg | $238 | In Stock | |
| 50 mg | Inquiry | Backorder |
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Purity:99.62%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Hamaudol, a chromone isolated from Saposhnikovia divaricata, exhibits analgesic and anti-inflammatory activities, demonstrating inhibitory effects on COX-1 and COX-2 with respective values of 0.30 and 0.57 mM. |
| Targets&IC50 | COX-1:0.30 mM, COX-2:57 mM |
| In vitro | The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth. From this extract, a new furanocoumarin named japoangelone and four furanocoumarin ethers of falcarindiol, named japoangelols A-D, were isolated together with caffeic acid methyl ester, four polyacetylenic compounds (panaxynol, falcarindiol, 8-O-acetylfalcarindiol, and (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol), eight coumarins (osthol, isoimperatorin, scopoletin, byakangelicin, xanthotoxin, bergapten, oxypeucedanin methanolate, and oxypeucedanin hydrate), and two chromones (3'-O-acetylHamaudol, and Hamaudol)[1] |
| Molecular Weight | 276.28 |
| Formula | C15H16O5 |
| Cas No. | 735-46-6 |
| Smiles | Cc1cc(=O)c2c(O)c3C[C@H](O)C(C)(C)Oc3cc2o1 |
| Relative Density. | 1.336 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: <10 mM  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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