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HexylHIBO

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Catalog No. T22840Cas No. 334887-43-3

HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.

HexylHIBO

HexylHIBO

🥰Excellent
Purity: 99.48%
Catalog No. T22840Cas No. 334887-43-3
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Pack SizePriceAvailabilityQuantity
1 mg$77In Stock
5 mg$178In Stock
10 mg$263In Stock
25 mg$595In Stock
50 mgInquiryIn Stock
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Purity:99.48%
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Product Introduction

Bioactivity
Description
HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.
Targets&IC50
mGlu1a:140 μM(Kb), mGlu5a:110 μM(Kb)
Chemical Properties
Molecular Weight256.3
FormulaC12H20N2O4
Cas No.334887-43-3
SmilesC(CCCCC)C1=C(CC(C(O)=O)N)ONC1=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
1eq. NaOH: 18.0 mg/mL (70.2 mM)
Solution Preparation Table
1eq. NaOH
1mg5mg10mg50mg
1 mM3.9017 mL19.5084 mL39.0168 mL195.0839 mL
5 mM0.7803 mL3.9017 mL7.8034 mL39.0168 mL
10 mM0.3902 mL1.9508 mL3.9017 mL19.5084 mL
20 mM0.1951 mL0.9754 mL1.9508 mL9.7542 mL
50 mM0.0780 mL0.3902 mL0.7803 mL3.9017 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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