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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $50 | 7-10 days | |
5 mg | $56 | 7-10 days | |
10 mg | $82 | 7-10 days | |
25 mg | $148 | 7-10 days | |
50 mg | $219 | 7-10 days | |
100 mg | $302 | 7-10 days | |
1 mL x 10 mM (in DMSO) | $65 | 7-10 days |
Description | Hoechst 34580 (HOE 34580), a cell-permeable fluorescent dye, is used for staining DNA and nuclei. |
In vitro | Hoechst 34580 is a good candidate for treating Alzheimer's disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580. |
Alias | HOE 34580 |
Molecular Weight | 451.57 |
Formula | C27H29N7 |
Cas No. | 23555-00-2 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 47 mg/mL (104.08 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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