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Product Introduction

Bioactivity

Description

Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.

Chemical Properties

Molecular Weight	354.38
Formula	C₂₀H₂₀NO₅
Cas No.	128397-41-1
Smiles	OC12C=3C(=CC4=C(C3)OCO4)CC[N+]1(C)CC=5C(C2)=CC=C6C5OCO6
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 45 mg/mL (126.98 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8218 mL	14.1091 mL	28.2183 mL	141.0915 mL
5 mM	0.5644 mL	2.8218 mL	5.6437 mL	28.2183 mL
10 mM	0.2822 mL	1.4109 mL	2.8218 mL	14.1091 mL
20 mM	0.1411 mL	0.7055 mL	1.4109 mL	7.0546 mL
50 mM	0.0564 mL	0.2822 mL	0.5644 mL	2.8218 mL
100 mM	0.0282 mL	0.1411 mL	0.2822 mL	1.4109 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitHydroprotopine