Shopping Cart
- Remove All
Your shopping cart is currently empty
Hydroxy Itraconazole
🥰Excellent
Catalog No. TQ0224Cas No. 112559-91-8
Alias R-63373
Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.
Hydroxy Itraconazole
🥰Excellent
Catalog No. TQ0224Alias R-63373Cas No. 112559-91-8
Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $393 | In Stock | |
| 5 mg | $817 | In Stock | |
| 10 mg | $1,344 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Hydroxy Itraconazole"
Dimethyl sulfoxide
Cited
Methyl Sulfoxide, DMSO
T034167-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
- $45
Size
QTY
CitedNeomycin sulfate Cited
Framycin sulfate
T09501405-10-3
Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.
- $43
Size
QTY
CitedSulfamethoxazole sodium
Ro 4-2130 sodium
T81394563-84-2
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic.
- $32
Size
QTY
Doxycycline Cited
Vibramycin, Doxytetracycline, Doxycyclinum, Doxiciclina
T1687564-25-0
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.
- $45
Size
QTY
CitedKanamycin sulfate
Ophtalmokalixan, Kanamycin monosulfate, Kanamycin A monosulfate
T079325389-94-0
Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.
- $41
Size
QTY
Ampicillin sodium Cited
Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral
T638669-52-3
Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium (Domicillin) inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan synthesis, a critical component of the bacterial cell wall.
- $50
Size
QTY
CitedDoxycycline (hyclate)
WC2031, Doxycycline hydrochloride hemiethanolate hemihydrate, Doxycycline hyclate
T1687L24390-14-5
Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor activity.
- $41
Size
QTY
Dehydroacetic acid sodium
Sodium dehydroacetate
T224274418-26-2
Dehydroacetic acid sodium (Sodium dehydroacetate) is the sodium salt of dehydroacetic acid, a bactericide and fungicide that is commonly used as a food preservative. Dehydroacetic acid sodium is a preservative that is used in the formulation of personal care products and cosmetics in order to extend the shelf-life by preventing microbial contamination.
- $31
Size
QTY
Methyl anthranilate
TN1925134-20-3
Methyl anthranilate is a natural product. Methyl anthranilate is a novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria
- $50
Size
QTY
Metronidazole Cited
Metronidazol, Flagyl, Anagiardil
T1079443-48-1
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
- $30
Size
QTY
CitedCrystal Violet Cited
Methyl Violet 10B, Hexamethylpararosaniline chloride, Gentian Violet, Basic Violet 3
T1343L548-62-9
Crystal Violet (Hexamethylpararosaniline chloride) is a triarylmethane dye that is a mixture of violet rosanilinis, with antibacterial, antifungal, and anthelmintic properties.
- $46
Size
QTY
CitedChitosan (MW 150000)
Poly(D-glucosamine), Deacetylated chitin, Chitosan
T17159012-76-4
Chitosan (MW 150000) (Deacetylated chitin) is a linear polysaccharide made up of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine.
- $42
Size
QTY
Select Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors. |
| In vitro | Hydroxy Itraconazole is considered to have antifungal effects in vitro. It contains a triazole ring in its structure and is capable of inhibiting the CYP3A enzyme. [1] |
| In vivo | Plasma concentrations of Hydroxy Itraconazole do not correlate well with ITZ doses, probably because the process of forming Hydroxy Itraconazole is saturated. Factors such as serum albumin and GFR affect the pharmacokinetics of ITZ and Hydroxy Itraconazole. When considering antifungal activity, it is important to look not only at plasma concentrations of ITZ, but also at plasma concentrations of Hydroxy Itraconazole. However, the pharmacokinetics of Hydroxy Itraconazole in immunocompromised patients receiving oral ITZ solutions are similar to those of ITZ. Therefore, since plasma concentrations of ITZ and Hydroxy Itraconazole are highly correlated, determining plasma concentrations of both should be sufficient from a clinical standpoint. [1] |
| Alias | R-63373 |
| Molecular Weight | 721.63 |
| Formula | C35H38Cl2N8O5 |
| Cas No. | 112559-91-8 |
| Smiles | O=C1N(N=CN1C2=CC=C(C=C2)N3CCN(C4=CC=C(OCC5OC(OC5)(C6=CC=C(Cl)C=C6Cl)CN7N=CN=C7)C=C4)CC3)C(C)C(O)C |
| Relative Density. | 1.44g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80.00 mg/mL (110.86 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Hydroxy Itraconazole | purchase Hydroxy Itraconazole | Hydroxy Itraconazole cost | order Hydroxy Itraconazole | Hydroxy Itraconazole chemical structure | Hydroxy Itraconazole in vivo | Hydroxy Itraconazole in vitro | Hydroxy Itraconazole formula | Hydroxy Itraconazole molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.