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JH-LPH-33 is a UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor with antimicrobial activity for the study of bacterial infections.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | 129 € | In Stock |
Description | JH-LPH-33 is a UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor with antimicrobial activity for the study of bacterial infections. |
Targets&IC50 | LpxH (Klebsiella pneumoniae):0.026 μM |
In vitro | The activity of JH-LPH-33 against Klebsiella pneumoniae LpxH and Escherichia coli LpxH exhibited IC50 values of 0.026 μM and 0.046 μM, respectively. JH-LPH-33 significantly inhibited bacterial growth at a concentration of 1.6 μg/mL, but its minimum inhibitory concentration (MIC) against E. coli exceeded 64 μg/mL. [1] |
Molecular Weight | 487.92 |
Formula | C21H21ClF3N3O3S |
Cas No. | 2414590-04-6 |
Smiles | O=C(N1C2=CC=C(C=C2CC1)S(=O)(=O)N3CCN(C4=CC(Cl)=CC(=C4)C(F)(F)F)CC3)C |
Relative Density. | 1.448 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | DMSO: 1.00 mg/mL (2.05 mM), Sonication is recommended | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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