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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $136 | 5 days |
Description | JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase (LpxH) inhibitor, exhibiting remarkable antibiotic activity with a minimal inhibitory concentration (MIC) value of 0.66 μg/mL. |
In vitro | JH-LPH-33 effectively suppresses bacterial proliferation, demonstrating potent inhibition at a concentration of 1.6 μg/mL, and exhibits a minimum inhibitory concentration (MIC) of >64 μg/mL against E. coli. Furthermore, it shows significant activity against LpxH enzymes, with IC50 values of 0.026 μM for K. pneumoniae LpxH and 0.046 μM for E. coli LpxH, respectively. |
Cas No. | 2414590-04-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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