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KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $143 | 35 days | |
1 mg | $268 | In Stock | |
5 mg | $987 | 35 days | |
10 mg | $1,770 | 35 days |
Description | KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components. |
In vitro | KOdiA-PC inhibited LPS-induced macrophage migration. [1] |
In vivo | In a mouse model of acute lung injury induced by intranasal injection of HKSA, intravenous injection of KOdiA-PC(10 mg/kg) increased HKSA-induced BAL protein content and cell count, as well as tissue expression of TNF-α, KC, IL1β and CCL2. And promoted blood vessel leakage in Evans Blue's lung infiltration monitoring. [2] |
Molecular Weight | 663.78 |
Formula | C32H58NO11P |
Cas No. | 439904-33-3 |
Smiles | [C@H](OC(CCCC(/C=C/C(O)=O)=O)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | PBS (pH7.2): 5.00 mg/mL (7.53 mM) DMSO: < 1 mg/mL (insoluble or slightly soluble) PBS (pH 7.2): 1.00 mg/mL (1.51 mM), Sonication is recommended. Ethanol: 10.00 mg/mL (15.07 mM), Sonication is recommended. DMF: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
PBS (pH7.2)/Ethanol
Ethanol
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