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KOdiA-PC

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Catalog No. T36172Cas No. 439904-33-3

KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.

KOdiA-PC

KOdiA-PC

😃Good
Catalog No. T36172Cas No. 439904-33-3
KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.
Pack SizePriceAvailabilityQuantity
500 μg$14335 days
1 mg$268In Stock
5 mg$98735 days
10 mg$1,77035 days
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Concentration:5.0 mg/mL
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Product Introduction

Bioactivity
Description
KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.
In vitro
KOdiA-PC inhibited LPS-induced macrophage migration. [1]
In vivo
In a mouse model of acute lung injury induced by intranasal injection of HKSA, intravenous injection of KOdiA-PC(10 mg/kg) increased HKSA-induced BAL protein content and cell count, as well as tissue expression of TNF-α, KC, IL1β and CCL2. And promoted blood vessel leakage in Evans Blue's lung infiltration monitoring. [2]
Chemical Properties
Molecular Weight663.78
FormulaC32H58NO11P
Cas No.439904-33-3
Smiles[C@H](OC(CCCC(/C=C/C(O)=O)=O)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH7.2): 5.00 mg/mL (7.53 mM)
DMSO: < 1 mg/mL (insoluble or slightly soluble)
PBS (pH 7.2): 1.00 mg/mL (1.51 mM), Sonication is recommended.
Ethanol: 10.00 mg/mL (15.07 mM), Sonication is recommended.
DMF: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
PBS (pH7.2)/Ethanol
1mg5mg10mg50mg
5 mM0.3013 mL1.5065 mL3.0130 mL15.0652 mL
Ethanol
1mg5mg10mg50mg
10 mM0.1507 mL0.7533 mL1.5065 mL7.5326 mL

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