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L-797,591 hydrochloride

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Catalog No. T27787L
Alias L-797,591 hydrochloride(217480-24-5 Free base)

L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride significantly enhanced p38 phosphorylation in cotransfected cells, and this effect was reversed in combination with AG1478.

L-797,591 hydrochloride

L-797,591 hydrochloride

🥰Excellent
Purity: 100%
Catalog No. T27787LAlias L-797,591 hydrochloride(217480-24-5 Free base)
L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride significantly enhanced p38 phosphorylation in cotransfected cells, and this effect was reversed in combination with AG1478.
Pack SizePriceAvailabilityQuantity
1 mg$400In Stock
5 mg$1,020In Stock
10 mg$1,540In Stock
25 mg$2,690In Stock
50 mg$3,180In Stock
100 mg$4,300In Stock
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Purity:100%
ee:100%
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Product Introduction

Bioactivity
Description
L-797,591 hydrochloride is active for somatostatin receptor isoform 1 (SSTR1). L-797,591 hydrochloride is commonly used in combination with AG1478 to enhance p-ERK5 expression in SSTR1 cells. L-797,591 hydrochloride significantly enhanced p38 phosphorylation in cotransfected cells, and this effect was reversed in combination with AG1478.
In vitro
L-797591 (10 nM; 1 h) reduced GLP-1-induced insulin secretion in RINm5F cells.[1]
AliasL-797,591 hydrochloride(217480-24-5 Free base)
Chemical Properties
Molecular Weight644.30
FormulaC38H50ClN5O2
SmilesO=C(N(CCC1=CC=CC=N1)CCC2=CC=CC=C2)N[C@@H](C(NCC(C)(C)CC(C)CCN)=O)CC3=CC=CC4=C3C=CC=C4.Cl
Relative Density.no data available
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (85.36 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5521 mL7.7604 mL15.5207 mL77.6036 mL
5 mM0.3104 mL1.5521 mL3.1041 mL15.5207 mL
10 mM0.1552 mL0.7760 mL1.5521 mL7.7604 mL
20 mM0.0776 mL0.3880 mL0.7760 mL3.8802 mL
50 mM0.0310 mL0.1552 mL0.3104 mL1.5521 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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