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Lenalidomide-OH is an analog of Lenalidomide, a cereblon ligand for E3 ubiquitin ligase (CRBN), used for CRBN protein recruitment. It is able to attach to protein ligands using linkers to form PROTAC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $39 | In Stock | |
50 mg | $59 | In Stock | |
100 mg | $88 | In Stock | |
1 mL x 10 mM (in DMSO) | $97 | In Stock |
Description | Lenalidomide-OH is an analog of Lenalidomide, a cereblon ligand for E3 ubiquitin ligase (CRBN), used for CRBN protein recruitment. It is able to attach to protein ligands using linkers to form PROTAC. |
In vitro | Lenalidomide-OH can be linked to a protein ligand via a linker to form PROTACs, which induce the ubiquitination-mediated degradation of cancer-promoting proteins [1]. |
Molecular Weight | 260.25 |
Formula | C13H12N2O4 |
Cas No. | 1416990-08-3 |
Smiles | O=C1N(CC=2C1=CC=C(O)C2)C3C(=O)NC(=O)CC3 |
Relative Density. | 1.498 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (42.27 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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