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Lipoxamycin hemisulfate

Lipoxamycin hemisulfate
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Purity:99.19%
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Lipoxamycin hemisulfate

Catalog No. T26308Cas No. 11075-87-9
Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
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Pack SizePriceAvailabilityQuantity
1 mg$147In Stock
2 mg$219In Stock
5 mg$369In Stock
10 mg$526In Stock
25 mg$792In Stock
50 mg$1,070In Stock
100 mg$1,430In Stock
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Product Introduction

Bioactivity
Description
Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
In vitro
Lipoxamycin hemisulfate shows antifungal activity against a panel of human pathogenic fungi with better potency against some of the Candida species (MIC = 0.25-16 µg/mL)[1].
In vivo
In Chinese hamster ovary cell mutant, Lipoxamycin hemisulfate is highly toxic in mice when applied subeutaneously or topically[1].
AliasLipoxamycin, sulfate (2:1), U-26146D, U26146D, U 26146D, Lipoxamycin
Chemical Properties
Molecular Weight843.08
FormulaC38H74N4O14S
Cas No.11075-87-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 36 mg/mL (42.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1861 mL5.9306 mL11.8613 mL59.3064 mL
5 mM0.2372 mL1.1861 mL2.3723 mL11.8613 mL
10 mM0.1186 mL0.5931 mL1.1861 mL5.9306 mL
20 mM0.0593 mL0.2965 mL0.5931 mL2.9653 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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