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Mal-PEG1-NHS ester
🥰Excellent
Catalog No. T15976Cas No. 1807518-72-4
Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]
Mal-PEG1-NHS ester
🥰Excellent
Purity: 98.19%
Catalog No. T15976Cas No. 1807518-72-4
Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $37 | In Stock | |
| 10 mg | $53 | In Stock | |
| 25 mg | $97 | In Stock | |
| 50 mg | $166 | In Stock | |
| 100 mg | $266 | In Stock | |
| 200 mg | $403 | In Stock |
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Diethylene glycol bis(p-toluenesulfonate)
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Diethylene glycol bis(p-toluenesulfonate) (Bis-Tos-PEG2) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
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Fmoc-8-amino-3,6-dioxaoctanoic acid
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1-Bromo-6-chlorohexane
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Pentaethylene glycol
3,6,9,12-Tetraoxatetradecane-1,14-diol
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Bis-Tos-PEG4
Tetraethylene glycol di(p-toluenesulfonate), PROTAC Linker 16, 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane
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Decaethylene glycol
HO-PEG10-OH
T150895579-66-8
Decaethylene glycol (HO-PEG10-OH) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
- $36
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DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
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Purity:98.19%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester] |
| In vitro | ADCs consist of an antibody attached to an ADC cytotoxin through an ADC linker. |
| Molecular Weight | 310.26 |
| Formula | C13H14N2O7 |
| Cas No. | 1807518-72-4 |
| Smiles | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O |
| Relative Density. | 1.48 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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