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MB05032
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Catalog No. T16020Cas No. 261365-11-1
Alias MB-05032, MB 05032
MB05032 is a potent fructose-,-bisphosphatase inhibitor that inhibits gluconeogenesis and reduces d-lactate-triggered ETosis.
MB05032
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Purity: 99.66%
Catalog No. T16020Alias MB-05032, MB 05032Cas No. 261365-11-1
MB05032 is a potent fructose-,-bisphosphatase inhibitor that inhibits gluconeogenesis and reduces d-lactate-triggered ETosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $112 | 5 days | |
| 25 mg | $613 | 6-8 weeks | |
| 50 mg | $797 | 6-8 weeks | |
| 100 mg | $1,390 | 6-8 weeks | |
| 1 mL x 10 mM (in DMSO) | $217 | 5 days |
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Purity:99.66%
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Product Introduction
Bioactivity
Chemical Properties
| Description | MB05032 is a potent fructose-,-bisphosphatase inhibitor that inhibits gluconeogenesis and reduces d-lactate-triggered ETosis. |
| Targets&IC50 | FBPase (human Liver):16 nM |
| In vivo | METHODS: To investigate the therapeutic effect of MB05032 on gluconeogenesis in type 2 diabetes, MB05032 was orally administered at different doses (3-300 mg/kg; once) to young and aged ZDF rats. RESULTS: MB05032 resulted in a dose-dependent decrease in blood glucose levels. |
| Alias | MB-05032, MB 05032 |
| Molecular Weight | 302.29 |
| Formula | C11H15N2O4PS |
| Cas No. | 261365-11-1 |
| Smiles | O=P(O)(O)C=1OC(=CC1)C=2N=C(SC2CC(C)C)N |
| Relative Density. | 1.47 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (132.32 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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