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MC-Gly-Gly-Phe

Catalog No. T18308Cas No. 1599440-15-9

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

MC-Gly-Gly-Phe

MC-Gly-Gly-Phe

Purity: 99.63%
Catalog No. T18308Cas No. 1599440-15-9
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
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10 mg$29In Stock
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Purity:99.63%
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Product Introduction

Bioactivity
Description
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).
Chemical Properties
Molecular Weight472.49
FormulaC23H28N4O7
Cas No.1599440-15-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 49 mg/mL (103.70 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1164 mL10.5822 mL21.1645 mL105.8223 mL
5 mM0.4233 mL2.1164 mL4.2329 mL21.1645 mL
10 mM0.2116 mL1.0582 mL2.1164 mL10.5822 mL
20 mM0.1058 mL0.5291 mL1.0582 mL5.2911 mL
50 mM0.0423 mL0.2116 mL0.4233 mL2.1164 mL
100 mM0.0212 mL0.1058 mL0.2116 mL1.0582 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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