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Methyl 5-hydroxypyridine-2-carboxylate

Catalog No. T40388Cas No. 30766-12-2

Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.

Methyl 5-hydroxypyridine-2-carboxylate

Methyl 5-hydroxypyridine-2-carboxylate

Purity: 98%
Catalog No. T40388Cas No. 30766-12-2
Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.
Pack SizePriceAvailabilityQuantity
200 mg$34In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:98%
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Product Introduction

Bioactivity
Description
Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.
In vitro
Methyl 5-hydroxypyridine-2-carboxylate (compound 2) inhibits NO in LPS-stimulated RAW264.7 and BV2 cells, with IC50 values of 115.67 and 118.80 μM, respectively, and exhibits no cytotoxic effects at concentrations ranging from 6.25 to 200 μM [1].
Chemical Properties
Molecular Weight153.14
FormulaC7H7NO3
Cas No.30766-12-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (326.50 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.5300 mL32.6499 mL65.2997 mL326.4986 mL
5 mM1.3060 mL6.5300 mL13.0599 mL65.2997 mL
10 mM0.6530 mL3.2650 mL6.5300 mL32.6499 mL
20 mM0.3265 mL1.6325 mL3.2650 mL16.3249 mL
50 mM0.1306 mL0.6530 mL1.3060 mL6.5300 mL
100 mM0.0653 mL0.3265 mL0.6530 mL3.2650 mL

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