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Moxipraquine is a novel 8-aminoquinolone compound with anti-infective activity against Trypanosoma cruzi. Moxipraquine effectively inhibited parasitemia but did not eradicate infections in mice or guinea pigs. Moxipraquine was effective against experimental infections of Leishmania major, Lactobacillus mexicanus, and Lactobacillus brasiliensis, but was Ineffective.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $162 | In Stock | |
5 mg | $390 | In Stock | |
10 mg | $590 | In Stock | |
25 mg | $943 | In Stock | |
50 mg | $1,280 | In Stock | |
100 mg | $1,730 | In Stock | |
500 mg | $3,460 | In Stock |
Description | Moxipraquine is a novel 8-aminoquinolone compound with anti-infective activity against Trypanosoma cruzi. Moxipraquine effectively inhibited parasitemia but did not eradicate infections in mice or guinea pigs. Moxipraquine was effective against experimental infections of Leishmania major, Lactobacillus mexicanus, and Lactobacillus brasiliensis, but was Ineffective. |
In vivo | Moxipraquine (5, 15, or 45 mg base/kg; oral; 14 days) was effective in suppressing parasitemia but did not eradicate the infection from mice or guinea pigs.[1] Moxipraquine (50 mg base/kg; oral; 5 times) was effective on experimental infections of Leishmania major, L. Mexicana mexicana, and L.brasiliensis panamensis but not L.b.brasiliensis.[1] |
Molecular Weight | 414.58 |
Formula | C24H38N4O2 |
Cas No. | 23790-08-1 |
Smiles | N(CCCCCCN1CCN(CCC(C)O)CC1)C=2C3=C(C=C(OC)C2)C=CC=N3 |
Storage | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 18.33 mg/mL (44.22 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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