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Necroptosis-IN-3
🥰Excellent
Catalog No. T64349Cas No. 547698-18-0
Alias Cyclohexanecarboxamide, N-(2-thienylmethyl)-
Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
Necroptosis-IN-3
🥰Excellent
Purity: 98.33%
Catalog No. T64349Alias Cyclohexanecarboxamide, N-(2-thienylmethyl)-Cas No. 547698-18-0
Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $35 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $103 | In Stock | |
| 25 mg | $208 | In Stock | |
| 50 mg | $323 | In Stock | |
| 100 mg | $467 | In Stock | |
| 200 mg | $648 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $56 | In Stock |
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Purity:98.33%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1. |
| In vitro | TNF-α-IN-8 (Compound 69) (0.030-100 μM; 24 h) inhibits TNF-α-induced necrosis in FADD-deficient human Jurkat T cells [1]. |
| Alias | Cyclohexanecarboxamide, N-(2-thienylmethyl)- |
| Molecular Weight | 223.33 |
| Formula | C12H17NOS |
| Cas No. | 547698-18-0 |
| Smiles | C(NCC1=CC=CS1)(=O)C2CCCCC2 |
| Relative Density. | 1.135 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (246.27 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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