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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $76 | In Stock | |
5 mg | $228 | In Stock | |
10 mg | $372 | In Stock | |
25 mg | $615 | In Stock | |
50 mg | $869 | In Stock | |
1 mL x 10 mM (in DMSO) | $223 | In Stock |
Description | Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
In vitro | Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcαμRI-mediated allergic reaction. We determined that 6-Methoxyluteolin inhibited anti-FcαμRI α± chain antibody (CRA-1)-induced histamine release, as well as elevation of intracellular calcium concentration [Ca2+]i in a dose-dependent manner. Moreover, the inhibitory effects of 6-Methoxyluteolin on the cell surface expression and the mRNA level of the FcαμRI α± chain were determined by flow cytometric analysis and reverse transcription-polymerase chain reaction (RTPCR), respectively. |
Alias | 6-Methoxyluteolin |
Molecular Weight | 316.26 |
Formula | C16H12O7 |
Cas No. | 520-11-6 |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 10 mg/mL (31.62 mM) ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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