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Nortriptyline
🥰Excellent
Catalog No. T73844Cas No. 72-69-5
Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation.
Nortriptyline
🥰Excellent
Purity: 99.8%
Catalog No. T73844Cas No. 72-69-5
Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $39 | In Stock | |
| 5 mg | $62 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $158 | In Stock | |
| 50 mg | $228 | In Stock | |
| 100 mg | $372 | In Stock | |
| 500 mg | $869 | In Stock |
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Purity:99.8%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Nortriptyline is an antidepressant compound that enhances corticosteroid sensitivity of blood T-cells in patients with chronic obstructive pulmonary disease (COPD) and may be used for smoking cessation. |
| In vitro | In human TCCSUP and mouse MBT-2 bladder cancer cells, Nortriptyline (at concentrations of 6.25 μM, 12.5 μM, 25 μM, 50 μM, and 100 μM; treatment durations of 24, 48, or 72 hours) exhibited cytotoxic effects on both TCCSUP and MBT-2 cells[3]. |
| In vivo | In adult male C3H/HeN mice (weighing 25-30 grams, aged 2-3 months) inoculated with MBT-2 cells, Nortriptyline (administered at doses of 10 or 20 mg/kg; via intraperitoneal injection; once daily; for three weeks) was able to suppress tumor growth in mice engrafted with MBT-2 cells[3]. |
| Molecular Weight | 263.38 |
| Formula | C19H21N |
| Cas No. | 72-69-5 |
| Smiles | C=1C=CC2=C(C1)C(=CCCNC)C=3C=CC=CC3CC2 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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