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PARP10-IN-3
🥰Excellent
Catalog No. T67932Cas No. 2225800-19-9
PARP10-IN-3 is a potent and selective mono-Adp-ribotransferase PARP10 inhibitor that inhibits human PARP10 (IC50:480 nM). PARP10-IN-3 also inhibited human PARP2 and human PARP15 with IC50 values of 1.7 μM.
PARP10-IN-3
🥰Excellent
Purity: 99.54%
Catalog No. T67932Cas No. 2225800-19-9
PARP10-IN-3 is a potent and selective mono-Adp-ribotransferase PARP10 inhibitor that inhibits human PARP10 (IC50:480 nM). PARP10-IN-3 also inhibited human PARP2 and human PARP15 with IC50 values of 1.7 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $31 | In Stock | |
| 5 mg | $48 | In Stock | |
| 10 mg | $81 | In Stock | |
| 25 mg | $163 | In Stock | |
| 50 mg | $263 | In Stock | |
| 100 mg | $419 | In Stock | |
| 500 mg | $955 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $53 | In Stock |
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Purity:99.54%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PARP10-IN-3 is a potent and selective mono-Adp-ribotransferase PARP10 inhibitor that inhibits human PARP10 (IC50:480 nM). PARP10-IN-3 also inhibited human PARP2 and human PARP15 with IC50 values of 1.7 μM. |
| Targets&IC50 | PARP1 (human):>100 μM, PARP14 (human):41 μM, TNKS2 (human):6.5 μM, PARP2 (human):1.7 μM, PARP10 (human):480 nM, PARP4 (human):7 μM, TNKS1(human):21 μM, PARP3 (human):>100 μM, PARP16 (human):>10 μM, PARP12 (human):>10 μM, PARP15 (human):1.7 μM |
| In vitro | PARP10-IN-3 exhibits an IC50 of 1-2 μM in HeLa-PARP10 cells as determined by colony formation assay (CFA).[1] |
| Molecular Weight | 256.26 |
| Formula | C14H12N2O3 |
| Cas No. | 2225800-19-9 |
| Smiles | O(C1=CC(C(N)=O)=CC=C1)C2=CC=C(C(N)=O)C=C2 |
| Relative Density. | 1.298 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 9 mg/mL (35.12 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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