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Parsaclisib hydrochloride

Parsaclisib hydrochloride
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Parsaclisib hydrochloride

Catalog No. T28297Cas No. 1995889-48-9
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.
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Pack SizePriceAvailabilityQuantity
25 mg$1,2301-2 weeks
50 mg$1,6101-2 weeks
100 mg$2,5701-2 weeks
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Product Introduction

Bioactivity
Description
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.
Targets&IC50
PI3Kδ:1 nM (IC50)
AliasParsaclisib HCl, INCB-50465, INCB 050465, INCB-050465, INCB050465 HCl, INCB 50465, INCB50465 HCl
Chemical Properties
Molecular Weight469.34
FormulaC20H23Cl2FN6O2
Cas No.1995889-48-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (191.76 mM)
H2O: Insoluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1307 mL10.6533 mL21.3065 mL106.5326 mL
5 mM0.4261 mL2.1307 mL4.2613 mL21.3065 mL
10 mM0.2131 mL1.0653 mL2.1307 mL10.6533 mL
20 mM0.1065 mL0.5327 mL1.0653 mL5.3266 mL
50 mM0.0426 mL0.2131 mL0.4261 mL2.1307 mL
100 mM0.0213 mL0.1065 mL0.2131 mL1.0653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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