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Pomaglumetad methionil hydrochloride
🥰Excellent
Catalog No. T61972Cas No. 635318-26-2
Alias LY2140023 hydrochloride
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) has research value in schizophrenia.
Pomaglumetad methionil hydrochloride
🥰Excellent
Purity: 99.01%
Catalog No. T61972Alias LY2140023 hydrochlorideCas No. 635318-26-2
Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) has research value in schizophrenia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $212 | In Stock | |
| 5 mg | $538 | In Stock | |
| 10 mg | $778 | In Stock | |
| 25 mg | $1,180 | In Stock | |
| 50 mg | $1,620 | In Stock |
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Purity:99.01%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pomaglumetad methionine hydrochloride (LY2140023 hydrochloride) is a methionine prodrug of LY404039 with oral activity. LY404039 is a selective mGlu2/3 receptor agonist. Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) has research value in schizophrenia. |
| In vitro | Pomaglumetad methionil (LY2140023) is a high-affinity substrate for peptide transporter 1 (PEPT1) with a Km of approximately 30 µM and demonstrates activity against [14C]Gly-Sar, exhibiting an IC50 of 0.018 mM[2]. |
| In vivo | Pomaglumetad methionil (LY2140023; orally; 3-300 mg/kg; once daily for 7 days) induces dose-dependent increases in the levels of dopamine metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) [1]. |
| Alias | LY2140023 hydrochloride |
| Molecular Weight | 402.87 |
| Formula | C12H19ClN2O7S2 |
| Cas No. | 635318-26-2 |
| Smiles | Cl.[H][C@@]12[C@@H](C(O)=O)[C@]1([H])S(=O)(=O)C[C@@]2(NC(=O)[C@@H](N)CCSC)C(O)=O |
Storage & Solubility Information
| Storage | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (55.8 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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