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Pomalidomide-PEG4-C2-NH2

🥰Excellent
Catalog No. T17916Cas No. 2225940-52-1
Alias E3 Ligase Ligand-Linker Conjugates 22, Cereblon Ligand-Linker Conjugates 8

Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.

Pomalidomide-PEG4-C2-NH2

Pomalidomide-PEG4-C2-NH2

🥰Excellent
Purity: 95.73%
Catalog No. T17916Alias E3 Ligase Ligand-Linker Conjugates 22, Cereblon Ligand-Linker Conjugates 8Cas No. 2225940-52-1
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$46In Stock
10 mg$68In Stock
25 mg$117In Stock
50 mg$175In Stock
100 mg$273In Stock
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Purity:95.73%
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Product Introduction

Bioactivity
Description
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.
AliasE3 Ligase Ligand-Linker Conjugates 22, Cereblon Ligand-Linker Conjugates 8
Chemical Properties
Molecular Weight492.52
FormulaC23H32N4O8
Cas No.2225940-52-1
SmilesO=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCOCCN
Relative Density.1.335 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (91.37 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0304 mL10.1519 mL20.3037 mL101.5187 mL
5 mM0.4061 mL2.0304 mL4.0607 mL20.3037 mL
10 mM0.2030 mL1.0152 mL2.0304 mL10.1519 mL
20 mM0.1015 mL0.5076 mL1.0152 mL5.0759 mL
50 mM0.0406 mL0.2030 mL0.4061 mL2.0304 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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