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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lysosomes of tumor cells, where it subsequently releases a small molecular compound that selectively eradicates TRAILR2-positive tumor cells, potentially leading to tumor remission [1]. |
Alias | AAJ8D6-PY-Val-Cit-MMAE |
Molecular Weight | 1446.79 |
Formula | C72H111N13O16S |
Cas No. | 2247398-68-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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