Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Streptomycin

🥰Excellent
Catalog No. T75320Cas No. 57-92-1
Alias Agrimycin, Agrept

Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections.

Streptomycin

Streptomycin

🥰Excellent
Catalog No. T75320Alias Agrimycin, AgreptCas No. 57-92-1
Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections.
Pack SizePriceAvailabilityQuantity
50 mg$30In Stock
100 mg$40In Stock
500 mg$92In Stock
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections.
In vitro
Streptomycin is a protein synthesis inhibitor that binds irreversibly to the small 16S rRNA of the 30S ribosome subunit, interfering with the binding of formyl-methionyl-trNA to the 30S subunit. It is often used in combination with penicillin in standard antibiotic mixtures to prevent bacterial infection in cell cultures. [1]
In vivo
Administration of Streptomycin (644 ± 26 mg/kg/ day) reduced the number of muscle fibers that increased membrane permeability after centrifugal contraction (ECC), but did not improve the degree of fiber swelling in existing EBD-positive fibers. [2]
AliasAgrimycin, Agrept
Chemical Properties
Molecular Weight581.57
FormulaC21H39N7O12
Cas No.57-92-1
SmilesO([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 160 mg/mL (275.12 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.7195 mL8.5974 mL17.1948 mL85.9742 mL
5 mM0.3439 mL1.7195 mL3.4390 mL17.1948 mL
10 mM0.1719 mL0.8597 mL1.7195 mL8.5974 mL
20 mM0.0860 mL0.4299 mL0.8597 mL4.2987 mL
50 mM0.0344 mL0.1719 mL0.3439 mL1.7195 mL
100 mM0.0172 mL0.0860 mL0.1719 mL0.8597 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Streptomycin | purchase Streptomycin | Streptomycin cost | order Streptomycin | Streptomycin chemical structure | Streptomycin in vivo | Streptomycin in vitro | Streptomycin formula | Streptomycin molecular weight