Streptomycin sulfate (Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.

Strain RB1 exhibits an increased susceptibility to streptomycin that correlates positively with the concentration of CV in the growth medium. Furthermore, as the CV concentration rises, both cytochrome aa3 levels and the bacterium's sensitivity to streptomycin simultaneously escalate. It is noteworthy that cytochrome aa3 plays a critical role in the uptake of streptomycin by B. subtilis[1]. Additionally, streptomycin affects tRNA selection, with resistance mutations predominantly located in protein S12; these mutations are typically associated with enhanced specificity in the tRNA selection process[2].