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Temocillin disodium
🥰Excellent
Catalog No. T40699Cas No. 61545-06-0
Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
Temocillin disodium
🥰Excellent
Catalog No. T40699Alias Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodiumCas No. 61545-06-0
Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $46 | In Stock | |
| 5 mg | $73 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections. |
| In vivo | The dosing regimen of Temocillin disodium is 200 mg/kg every 4 or 6 hours, which significantly reduces the bacterial counts of both strains in the kidneys, with no significant difference observed between the parental strain and its transconjugant. [2] |
| Alias | Temopen disodium, Negaban disodium, BRL17421 disodium, BRL 17421 disodium |
| Molecular Weight | 458.42 |
| Formula | C16H16N2Na2O7S2 |
| Cas No. | 61545-06-0 |
| Smiles | CO[C@@]1(NC(=O)C(C(=O)[O-])c2ccsc2)C(=O)N2[C@@H](C(=O)[O-])C(C)(C)S[C@@H]21.[Na+].[Na+] |
| Relative Density. | 1.6g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 200 mg/mL (436.28 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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