Shopping Cart
- Remove All
Your shopping cart is currently empty
Tesidolumab
Catalog No. T76831Cas No. 1531594-08-7
Alias LFG316
Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.
Tesidolumab
Tesidolumab
Catalog No. T76831Alias LFG316Cas No. 1531594-08-7
Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $198 | In Stock | |
| 5 mg | $496 | In Stock | |
| 10 mg | $828 | In Stock | |
| 25 mg | $1,230 | In Stock | |
| 50 mg | $1,650 | In Stock | |
| 100 mg | $2,230 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Tesidolumab"
3-Phenoxybenzaldehyde
T6438839515-51-0
3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.
- $29
Size
QTY
Dexamethasone
Cited
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
ADC CytotoxinAntibacterialAntibioticAutophagyComplement SystemGlucocorticoid ReceptorIL ReceptorMitophagySARS-CoV
- $29
Size
QTY
CitedCyclosporin A Cited
Cyclosporine A, Cyclosporine, Ciclosporin
T094559865-13-3
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM).
- $36
Size
QTY
CitedIptacopan hydrochloride
LNP023 hydrochloride, Iptacopan HCl
T91891646321-63-2In house
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
- $155
Size
QTY
ADH-503
GB1275
T77762055362-74-6
ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist that can lead to repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhancement of dendritic cell responses.
- $48
Size
QTY
BCX 1470 hydrochloride
BCX1470 HCl, BCX 1470 hydrochloride(217099-43-9 Free base)
T13568LIn house
BCX 1470 hydrochloride is a potent serine protease inhibitor with anti-inflammatory activity that inhibits the ester hydrolysis and haemolytic activity of factor D and C1s, and can be used to study oedema.
- $139
Size
QTY
EG01377 2HCl
EG01377 2HCl(2227996-00-9 Free base)
T11154L2749438-61-5In house
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.EG01377 exhibits anti-angiogenic, antimigratory and antitumor activities.
- $148
Size
QTY
CP-289
T601611349637-14-4
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
- $117
Size
QTY
Complement C5-IN-1
T108632365402-67-9In house
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
- $155
Size
QTY
SB290157 trifluoroacetate
T128511140525-25-2
SB290157 trifluoroacetate is a potent and selective antagonist of the C3a receptor, with an IC50 of 200 nM.
- $43
Size
QTY
CP-447697
T601511092847-21-6
CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.
- $45
Size
QTY
Complement factor D-IN-2
T383321903742-34-6
Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.
- $189
Size
QTY
Select Batch
Concentration:9.47 mg/mL
Purity:99.72% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Tesidolumab (LFG316) is a fully human IgG1/λ anti-C5 monoclonal antibody. Tesidolumab (LFG316) has an inhibitory effect on crovalimab and C5, blocking the cutting of C5 and preventing the subsequent formation of membrane attack complex, which can be used to study extravascular hemolysis. |
| In vitro | Tesidolumab (LFG316) has a half-life of approximately 9 days in humans and binds to a unique epitope distant from Arg 885, differentiating it from eculizumab and ravulizumab in its binding site[1]. |
| Alias | LFG316 |
| Molecular Weight | 142 kDa (average) |
| Cas No. | 1531594-08-7 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Tesidolumab | purchase Tesidolumab | Tesidolumab cost | order Tesidolumab | Tesidolumab in vitro | Tesidolumab molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.