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Thalidomide-O-amido-C4-N3
🥰Excellent
Catalog No. T15189Cas No. 2098488-36-7
Alias E3 ligase Ligand-Linker Conjugates 18, Cereblon Ligand-Linker Conjugates 4
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
Thalidomide-O-amido-C4-N3
🥰Excellent
Purity: 97.01%
Catalog No. T15189Alias E3 ligase Ligand-Linker Conjugates 18, Cereblon Ligand-Linker Conjugates 4Cas No. 2098488-36-7
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $51 | In Stock | |
| 5 mg | $83 | In Stock | |
| 10 mg | $122 | In Stock | |
| 25 mg | $197 | In Stock | |
| 50 mg | $298 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $97 | In Stock |
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Thalidomide-5-OH
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Thalidomide-O-COOH
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Thalidomide-O-COOH (Cereblon ligand 3) is a Thalidomide-based Cereblon ligand utilized for recruiting the CRBN protein and can be linked to a protein ligand via a linker to create PROTACs.
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Purity:97.01%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker. |
| Alias | E3 ligase Ligand-Linker Conjugates 18, Cereblon Ligand-Linker Conjugates 4 |
| Molecular Weight | 428.4 |
| Formula | C19H20N6O6 |
| Cas No. | 2098488-36-7 |
| Smiles | O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCN=[N+]=[N-])=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (93.37 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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