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Thiolutin

Catalog No. T67708Cas No. 87-11-6
Alias Acetopyrrothin

Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly.

Thiolutin

Thiolutin

Purity: 98.00%
Catalog No. T67708Alias AcetopyrrothinCas No. 87-11-6
Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly.
Pack SizePriceAvailabilityQuantity
1 mg$122In Stock
5 mg$297In Stock
10 mg$488In Stock
25 mg$958In Stock
50 mg$1,330In Stock
100 mg$1,790In Stock
1 mL x 10 mM (in DMSO)$336In Stock
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Purity:98.00%
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Product Introduction

Bioactivity
Description
Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly.
AliasAcetopyrrothin
Chemical Properties
Molecular Weight228.29
FormulaC8H8N2O2S2
Cas No.87-11-6
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 4.5 mg/mL (19.71 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3804 mL21.9020 mL43.8039 mL219.0197 mL
5 mM0.8761 mL4.3804 mL8.7608 mL43.8039 mL
10 mM0.4380 mL2.1902 mL4.3804 mL21.9020 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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