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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $223 | In Stock | |
2 mg | $328 | In Stock | |
5 mg | $557 | In Stock | |
10 mg | $812 | In Stock | |
25 mg | $1,230 | Backorder | |
50 mg | $1,670 | Backorder | |
100 mg | $2,260 | Backorder |
Description | Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor |
Cell Research | Objective: To validate that IL-6 signaling is essential for TAM (tumor-associated macrophages)-enhanced CSC (cancer stem cells) function. Concentrations: 5 μg/ml. Incubation Time: 72 h. Method: For co-culture experiments, 12-well Transwell chambers were used with 2×105 HepG2 or Hep3B cells seeded in the lower chamber one day before co-culture and either 5×105 or 1×106 TAMs added in the upper chamber. Tocilizumab or human IgG antibody were added in indicated experiments to selected wells. After 24 to 72 hours, HCC cells and CD14+ TAM cells were collected separately for analysis. Cells:HepG2 cell lines, TAMs isolated from HCCs (hepatocellular carcinoma) |
Molecular Weight | 148 kDa |
Cas No. | 375823-41-9 |
Storage | store at -20°C | Shipping with blue ice. |
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