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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7527 | Frentizole | Beta Amyloid | |
Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction | |||
T35664 | Tetracosactide acetate | Others | |
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland. | |||
T12783 | RWJ 50271 | Integrin | |
RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells). | |||
T10722 | CD80-IN-3 | Bombesin Receptor | |
CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM). | |||
T9706 | BTK inhibitor 17 | BTK | |
BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies. | |||
T1846 | Y-320 | Y320 | IL Receptor , Lipase , Interleukin |
Y-320 is a new phenylpyrazoleanilide immunomodulator. | |||
T9911 | Tocilizumab | Interleukin | |
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor | |||
T11699 | J-113863 | CCR | |
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor... | |||
T1421 | Aceclofenac | Preservex,Airtal | COX |
Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties. | |||
T0291 | Flurbiprofen | dl-Flurbiprofen | Apoptosis , COX , MRP |
Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE. | |||
T17258 | WRG-28 | Discoidin Domain Receptor (DDR) | |
WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) | |||
T13951 | UCB-9260 | TNF | |
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer. | |||
T4196 | Betahistine EP Impurity C | NSC19005 | Others , Histamine Receptor |
Betahistine EP Impurity C (NSC19005) is structurally related to Betahistine. Betahistine EP Impurity C is a dimer of Betahistine. | |||
T8003 | Methotrexate disodium | Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate | |
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor | |||
T4561 | Tiaprofenic acid | Tiaprofensaeure,Acido tiaprofenico,Surgam | Others , COX |
Tiaprofenic acid (Acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain. | |||
T4195 | Betahistine | PT 9 base,Vasomotal,Serc base | Histamine Receptor |
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... | |||
T8550 | NDMC101 | Others , NF-κB , Proteasome | |
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity. | |||
T0246 | Betahistine dihydrochloride | PT-9,Betahistine 2HCl | Histamine Receptor |
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. | |||
T9027 | CA-4948 | Emavusertib | IRAK , FLT |
CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity. | |||
T60012 | HS-243 | IRAK , MAPK , CDK | |
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity. | |||
T1780 | Parecoxib | SC 69124,Vorth-P,Valus-P | COX |
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor. | |||
T15199 | Edicotinib | JNJ-527,JNJ-40346527 | c-Fms , FLT , CSF-1R , c-Kit |
Edicotinib (JNJ-527) is a brain penetrant and orally active inhibitor of the colony-stimulating factor-1 receptor (IC50: 3.2 nM). It shows less inhibitory effects on KIT and FLT3 (IC50: 20 nM and 190 nM). It has the pote... | |||
T21334 | Bucillamine | DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019 | VEGFR , Antioxidant |
Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF. Bucillamine is an orally active sulfhydryl donor and antioxidant with antirheumatic and... | |||
T1485 | Methotrexate | NCI-C04671,WR19039,Amethopterin,CL14377 | Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate |
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and v... | |||
T20168 | Aurothiomalate sodium | Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate | Others , PKC |
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ... | |||
T6933 | Peficitinib | ASP015K,JNJ-54781532 | Tyrosine Kinases , JAK |
Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3. | |||
T15253 | CCX354 | CCR1 antagonist 1,CCX-354,CCX 354 | CCR |
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis. | |||
T15420 | GS-9901 | PI3K | |
GS-9901 is a highly selective and orally active inhibitor of PI3Kδ (IC50: 1 nM). It also has the potential to treat rheumatoid arthritis. | |||
T27864 | LX-2931 | LX 3305,LX2931,LX-3305,ACB20034,LX 2931,LX3305 | S1P Receptor |
LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis. | |||
T19641 | Epirizole | DA 398,Mepirizole,DA398,Mebron,Methopyrimazole,Dalex,DA-398 | Others |
Epirizole (Mebron) shows antipyretic, analgesic, and anti-inflammatory activity and can be used in studies about chronic rheumatoid arthritis. | |||
T1159 | Leflunomide | SU101,RS-34821,HWA486 | Others , Dehydrogenase , AhR |
Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. | |||
T11022 | DHODH-IN-13 | Dehydrogenase | |
DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis. | |||
T76888 | Quetmolimab | E-6011,KANAb 001 | Others |
Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis. | |||
T7534 | Teriflunomide | A 77-1726 | Others |
Teriflunomide (A 77-1726) is the principal active metabolite of leflunomide, an approved therapy for rheumatoid arthritis and multiple sclerosis. | |||
T0693 | Niflumic acid | Nifluril,Forenol,Landruma | Others , Phospholipase , Chloride channel , COX , Monocarboxylate transporter , UGT |
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis. | |||
T67842 | ERG240 | EGR240 | Others |
ERG240 is an inhibitor of branched-chain amino acid aminotransferase 1 (BCAT1). ERG240 can be used for the research of rheumatoid arthritis, cancer, and bone disease. | |||
T6321 | Tofacitinib | Tasocitinib,CP-690550 | ROCK , Apoptosis , JAK , Src |
Tofacitinib (Tasocitinib) is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis. | |||
T76775 | Fezakinumab | ILV 094 | Interleukin |
Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related conditions such as psoriasis, rheumatoid arthritis and atopic dermat... | |||
T11023 | DHODH-IN-14 | Dehydrogenase | |
DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726. DHODH-IN-14 is a dihydroorotate dehydrogenase (DHODH) inhibitor IC50 0.49 μM mouse liver DHODH. DHODH-IN-14 can be used for rheumatoid arthritis. | |||
T77601 | (2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid | GPR | |
(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid is a prostaglandin-like CRTH2 antagonist with an IC50 < 10 μM, which can be used in studies of rhinitis, COPD, rheumatoid arthritis, eczema and con... | |||
T9034 | MK2-IN-3 | MK2 Inhibitor III | MAPK |
MK2-IN-3 (MK2 Inhibitor III) is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis | |||
T26861 | BMS-817399 | BMS817399 | CCR |
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis. | |||
T27312 | Fentiazac | Donorest,Flogene,BR-700 | Others |
Fentiazac(BR-700) is an orally active nonsteroidal alkanoic acid derivative with significant analgesic, anti-inflammatory, and antipyretic activity.Fentiazac is used in the study of inflammatory diseases such as rheumato... | |||
T9529 | TAK-020 | BTK | |
TAK-020 is a potent covalent inhibitor of Btk with potential antitumor activity for the study of rheumatoid arthritis and immune-related diseases. | |||
T20763 | Betamethasone disodium phosphate | Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616 | Others |
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory activity that promotes the polarization of M1 to M2 macrophages by decreasing the secretion of pro-in... | |||
T1303 | Auranofin | SKF-39162 | Others , SARS-CoV , Antibacterial |
Auranofin (SKF-39162) is an antirheumatic agent, is used to treat rheumatoid arthritis, improves arthritis symptoms including painful or tender and swollen joints and morning stiffness. | |||
T9921 | Infliximab | TNF | |
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis. | |||
T37445 | Etanercept | TNF | |
Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TN... | |||
T76711 | Golimumab | MK-8259,SCH 900259,CNTO-148 | TNF |
Golimumab (CNTO-148) is a potent humanized anti-TNFα IgG1κ monoclonal antibody.Golimumab has anti-inflammatory and anticancer activity, inhibits the production of IL-6 and IL-1β, and induces apoptosis.Golimumab can be us... | |||
T0219 | Valdecoxib | SC 65872 | COX |
Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is classified as a nonsteroidal anti-inflammatory drug, or N... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2791 | Pectolinarin | Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin | |
Pectolinarin is a Cirsium isolate with anti-inflammatory activity. | |||
T8689 | Chloroquine | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy | |
Chloroquine is a Toll-like receptor inhibitor that inhibits autophagy. Chloroquine has anti-malarial and anti-inflammatory activity and is widely used in the treatment of malaria and rheumatoid arthritis. Chloroquine als... | |||
T5029 | Oxaceprol | N-Acetyl-L-hydroxyproline | Others |
Oxaceprol (N-Acetyl-L-hydroxyproline) is an established therapeutic agent for osteoarthritis. | |||
T0983 | Penicillamine | d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine | Antibiotic |
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a... | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T3136 | Methylcobalamin | CH3-B12,Methyl vitamin B12,Methycobal,Brassinolide,Vancomin,Cobametin | Endogenous Metabolite |
Methylcobalamin (Brassinolide) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's ... | |||
T1188 | Mizoribine | Bredinin,NSC 289637,HE 69 | HCV Protease , SARS-CoV , Tyrosinase |
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. | |||
TC0036 | Compound Lup-20(29)-en-3-yl acetate | IL Receptor , VEGFR , Others , TNF , COX | |
Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B. | |||
T2598 | Thymopentin | TP5 | Estrogen/progestogen Receptor , Endogenous Metabolite |
Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. Thymopentin (TP5) is an immunomodulator which has been studied for possibl... | |||
T13808 | P-Coumaric Acid Ethyl Ester | Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate | Others , Drug Metabolite |
p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato... | |||
T3662 | Eleutheroside E | NF-κB | |
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ... | |||
T6S1885 | Benzoylmesaconine | Mesaconine 14-benzoate | Others |
Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activi... | |||
T5S1982 | Periplocin | Periplocoside | Apoptosis , Others |
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato... | |||
T6S1784 | Brazilin | Natural Red 24,Braziletto,Brasilin,Superbresiline | Apoptosis , Others , AMPK , Autophagy |
1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific sign... | |||
T5S1895 | Norisoboldine | Laurelliptine,(+)-Laurelliptine | MAPK , Adenosine Receptor |
1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo... | |||
TN2539 | 1beta-Hydroxyalantolactone | IL Receptor , TNF | |
1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti... | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T6S1684 | 8-Gingerol | Antioxidant , Antibacterial , TRP/TRPV Channel | |
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic... | |||
T81975 | Kopsininic acid | ||
Kopsininic acid, a natural product isolated from Kopsia hainanensis, has potential applications in researching rheumatoid arthritis, pharyngitis, tonsillitis, and edema [1]. | |||
T75433 | Norisoboldine hydrochloride | ||
Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ... | |||
TN3741 | Cyclocurcumin | TNF , ROS | |
Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It m... | |||
TN3144 | 6,4'-Dihydroxy-7-methoxyflavanone | 檀木 | ERK , IL Receptor , Antioxidant , TNF , NF-κB , MAPK , Prostaglandin Receptor , JNK , Autophagy |
6,4'-Dihydroxy-7-methoxyflavanone is a biologically active compound isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) with antioxidant, anti-inflammatory and neuroprotective effects. 6,4'-Dihydroxy... | |||
T83117 | Angeloylbinankadsurin A | ||
Angeloylbinankadsurin A (compound 7), an anti-rheumatoid arthritis (RA) agent, can be extracted from the EtOAc and CH2Cl2 extracts of Black Tiger Beard. It displays inhibitory effects on RA-FLS cells with an IC50 of 11.7... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00995 | Serpin H1 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is th... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-02970 | CXCL10 Protein, Human, Recombinant | Human | E. coli |
(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple... | |||
TMPY-01371 | IL-17RA Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret... | |||
TMPY-02900 | IL-17A Protein, Mouse, Recombinant | Mouse | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-02886 | IL-17A Protein, Human, Recombinant | Human | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-00021 | PADI4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-00740 | SDF-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-04902 | Complement C5a Protein, Mouse, Recombinant | Mouse | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-02590 | HMGB1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas... | |||
TMPY-02591 | SDF-1 Protein, Human, Recombinant | Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-01848 | HMGB1 Protein, Human, Recombinant (aa 1-215, His) | Human | HEK293 |
High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas... | |||
TMPY-02820 | SDF-1 Protein, Human, Recombinant (isoform a) | Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f... | |||
TMPY-05057 | Complement C5 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-00653 | Complement C5 Protein, Human, Recombinant (Complement C5a) | Human | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPJ-01444 | IL-17A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Human Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ... | |||
TMPJ-00532 | PADI4 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyz... | |||
TMPK-01117 | OSCAR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n... | |||
TMPK-01092 | OSCAR Protein, Human, Recombinant (hFc) | Human | HEK293 |
Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n... | |||
TMPJ-01312 | TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it... | |||
TMPK-01329 | ANGPTL4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an... | |||
TMPK-00172 | B7-H4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A solu... | |||
TMPJ-00191 | FSTL1 Protein, Human, Recombinant | Human | E. coli |
Follistatin-Related Protein 1 (FSTL1) is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain, and one VWFC domain. Its functional significance in physiological and pat... | |||
TMPK-01378 | IL-12B Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.... | |||
TMPJ-00658 | CYR61/CCN1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein ... | |||
TMPJ-00202 | CD157 Protein, Human, Recombinant (hFc) | Human | Human Cells |
The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow str... | |||
TMPJ-00621 | LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, His) | Rhesus Macaque | Human Cells |
LILRB1, also known as CD85j and ILT2, is a transmembrane glycoprotein in the LILR immunoregulatory protein family. LILRB1 is expressed on NK cells that have expanded in response to acute HCMV infection. LILRB1 exhibits c... | |||
TMPJ-01110 | IRF5 Protein, Human, Recombinant (His) | Human | E. coli |
Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it ... | |||
TMPY-02319 | Galectin-3 Protein, Human, Recombinant | Human | E. coli |
LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain an... | |||
TMPY-02556 | FSTL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a mu... | |||
TMPJ-00909 | IL-1RA Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and int... | |||
TMPY-02458 | IL-1F8 Protein, Human, Recombinant | Human | E. coli |
Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines inclu... | |||
TMPY-02583 | IL-1F8 Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines inclu... | |||
TMPY-02817 | IL-1F8 Protein, Human, Recombinant (His) | Human | E. coli |
Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines inclu... | |||
TMPY-04943 | CXCL10 Protein, Rat, Recombinant (His) | Rat | Yeast |
(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple... | |||
TMPY-02965 | MMP-19 Protein, Human, Recombinant | Human | E. coli |
MMP19, also known as RASI-1, is a member of the peptidase M1A family. It contains 4 hemopexin-like domains and is expressed in the mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate... | |||
TMPJ-00981 | PTX3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory... | |||
TMPY-05118 | CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-06430 | CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-06282 | CD30/TNFRSF8 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-05737 | CD30/TNFRSF8 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-00725 | COMP Protein, Human, Recombinant (His) | Human | HEK293 |
Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein i... | |||
TMPY-04287 | IL-22RA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPY-05443 | CD30/TNFRSF8 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-04286 | IL-22RA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal... | |||
TMPY-00613 | FSTL1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a mu... | |||
TMPY-02952 | SIAE Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th... | |||
TMPY-01106 | FSTL1 Protein, Human, Recombinant (His) | Human | HEK293 |
Follistatin-related protein 1 (FSTL1) is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a mu... | |||
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530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening. | |||
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A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS; | |||
L2540 | Gut Microbial Metabolite Library | 614 compounds | |
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS; |