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Sirukumab

🥰Excellent
Catalog No. T76826Cas No. 1194585-53-9
Alias CNTO-136, CNTO136

Sirukumab (CNTO-136) is a selective humanized monoclonal antibody binding to Interleukin-6 (IL-6), inhibiting IL-6-mediated signal transduction and activation of transcription factors. It is used in lupus nephritis and rheumatoid arthritis research.

Sirukumab

Sirukumab

🥰Excellent
Catalog No. T76826Alias CNTO-136, CNTO136Cas No. 1194585-53-9
Sirukumab (CNTO-136) is a selective humanized monoclonal antibody binding to Interleukin-6 (IL-6), inhibiting IL-6-mediated signal transduction and activation of transcription factors. It is used in lupus nephritis and rheumatoid arthritis research.
Pack SizePriceAvailabilityQuantity
1 mg$288In Stock
5 mg$780In Stock
10 mg$1,180In Stock
25 mg$1,780In Stock
50 mg$2,380In Stock
100 mg$3,230In Stock
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Concentration:8.05 mg/mL
Purity:>95%
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Product Introduction

Bioactivity
Description
Sirukumab (CNTO-136) is a selective humanized monoclonal antibody binding to Interleukin-6 (IL-6), inhibiting IL-6-mediated signal transduction and activation of transcription factors. It is used in lupus nephritis and rheumatoid arthritis research.
AliasCNTO-136, CNTO136
Chemical Properties
Molecular Weight144.6 (kDa)
Cas No.1194585-53-9
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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