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Ozoralizumab
🥰Excellent
Catalog No. T77126Cas No. 1167985-17-2
Alias TS-152, ATN-103
Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis.
Ozoralizumab
Ozoralizumab
🥰Excellent
Purity: 95.6% (SEC-HPLC)
Catalog No. T77126Alias TS-152, ATN-103Cas No. 1167985-17-2
Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $328 | In Stock | |
| 5 mg | $859 | In Stock | |
| 10 mg | $1,270 | In Stock | |
| 25 mg | $1,890 | In Stock | |
| 50 mg | $2,550 | In Stock |
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Concentration:6.19 mg/mL
Purity:95.6% (SEC-HPLC)
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Ozoralizumab binds human serum albumin and can be used to study rheumatoid arthritis. |
| In vitro | METHODS: Ozoralizumab (ATN-103) (0.1-1000pM) was used to treat L929 cells and its high TNFα neutralizing potency was determined. RESULTS: Ozoralizumab (ATN-103) has high TNFα neutralizing potency, with very similar binding and dissociation properties, and KD values for human TNFα and monkey TNFα are 20.2 pM and 16.1 pM, respectively. [1] |
| In vivo | METHODS: Tg197 mice were injected subcutaneously with 1 mg/kg dose of Ozoralizumab (ATN-103) twice weekly to evaluate the formation of ADA against each anti-TNFα antibody and the effect of long-term administration of these anti-TNFα antibodies on TNFα-mediated TNFα in Tg197 mice. Efficacy of polyarthritis. RESULTS: Ozoralizumab (ATN-103) significantly and comparably reduced arthritis scores. [1] |
| Alias | TS-152, ATN-103 |
| Molecular Weight | 38.44 kDa |
| Cas No. | 1167985-17-2 |
Storage & Solubility Information
| Storage | store at low temperature | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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