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Triamcinolone hexacetonide
🥰Excellent
Catalog No. T17162Cas No. 5611-51-8
Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a highly potent glucocorticoid receptor (GR) agonist for the study of auto-reactive pericarditis and diabetic macular edema.
Triamcinolone hexacetonide
🥰Excellent
Catalog No. T17162Cas No. 5611-51-8
Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a highly potent glucocorticoid receptor (GR) agonist for the study of auto-reactive pericarditis and diabetic macular edema.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $31 | In Stock | |
| 10 mg | $48 | In Stock | |
| 25 mg | $85 | In Stock | |
| 50 mg | $127 | In Stock | |
| 100 mg | $189 | In Stock | |
| 200 mg | $278 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $37 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a highly potent glucocorticoid receptor (GR) agonist for the study of auto-reactive pericarditis and diabetic macular edema. |
| In vivo | Triamcinolone hexacetonide exhibited significant protective effects in a chemically induced model of articular cartilage damage, and this effect was dose-dependent. Guinea pigs injected with the drug exhibited significantly reduced fibrosis and bone spur formation. Triamcinolone hexacetonide injected into the ipsilateral knee of rabbits after partial lateral meniscectomy and severance of the metatarsophalangeal ligament and fibular collateral ligament reduced chondrocyte cloning, cell loss, bone spur formation, and fibrosis. [1] In addition, the half-life of commercially available Triamcinolone hexacetonide in the vitreous humor is twice as long as that of regular Triamcinolone hexacetonide. [2] Localized application of Triamcinolone hexacetonide at the site of lingual nerve injury has been shown to produce beneficial changes such as reduced mechanical sensitivity and promotion of nerve regeneration. [3] |
| Molecular Weight | 532.64 |
| Formula | C30H41FO7 |
| Cas No. | 5611-51-8 |
| Smiles | C(COC(CC(C)(C)C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H] |
| Relative Density. | 1.24 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (56.32 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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