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Werner syndrome RecQ helicase-IN-4

Name: Werner syndrome RecQ helicase-IN-4
Brand: TargetMol
SKU: T72110
Rating: 4.5 (1 reviews)

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Catalog No. T72110Cas No. 2869954-53-8

Werner syndrome RecQ helicase-IN-4 is a potent, orally active inhibitor of Werner syndrome RecQ helicase (WRN) with an IC50 of 0.06 µM, exhibiting antiproliferative and anticancer activities.

Werner syndrome RecQ helicase-IN-4

😃Good

Catalog No. T72110Cas No. 2869954-53-8

Werner syndrome RecQ helicase-IN-4 is a potent, orally active inhibitor of Werner syndrome RecQ helicase (WRN) with an IC50 of 0.06 µM, exhibiting antiproliferative and anticancer activities.

Pack Size	Price	Availability
25 mg	$1,670	6-8 weeks
50 mg	$2,180	6-8 weeks
100 mg	$2,800	6-8 weeks

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Product Introduction

Bioactivity

Description

Werner syndrome RecQ helicase-IN-4 is a potent, orally active inhibitor of Werner syndrome RecQ helicase (WRN) with an IC50 of 0.06 µM, exhibiting antiproliferative and anticancer activities.

Chemical Properties

Molecular Weight	666.65
Formula	C₃₂H₃₃F₃N₈O₅
Cas No.	2869954-53-8

Storage & Solubility Information

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Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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