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Wighteone
🥰Excellent
Catalog No. TN5254Cas No. 51225-30-0
Alias Erythrinin B, 6-Isopentenylgenistein
Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer.
Wighteone
🥰Excellent
Purity: 98.95%
Catalog No. TN5254Alias Erythrinin B, 6-IsopentenylgenisteinCas No. 51225-30-0
Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $73 | In Stock | |
| 5 mg | $125 | In Stock | |
| 10 mg | $208 | In Stock | |
| 25 mg | $415 | In Stock | |
| 50 mg | $665 | In Stock |
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Purity:98.95%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer. |
| In vitro | The limitations of currently available antifungal agents and the rapid emergence of drug-resistant strains necessitate more efficient approaches to screening and developing novel antifungal drugs. METHODS AND RESULTS: The antifungal activity of the natural products of a series of plants was evaluated and Wighteone, 5, 7, 4'-trihydroxy-6-(gamma,gamma-dimethylallyl)isoflavone showed excellent anti-yeast activity (MIC against Saccharomyces cerevisiae was 4 microg/ml). METHODS AND RESULTS: Transcriptome profiling of Wighteone-treated S. cerevisiae indicated that Wighteone is different from commonly used antifungal compounds in its mode of action. |
| Alias | Erythrinin B, 6-Isopentenylgenistein |
| Molecular Weight | 338.35 |
| Formula | C20H18O5 |
| Cas No. | 51225-30-0 |
| Smiles | O=C1C(=COC2=CC(O)=C(C(O)=C12)CC=C(C)C)C=3C=CC(O)=CC3 |
| Relative Density. | 1.351g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (236.44 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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