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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $73 | In Stock | |
5 mg | $125 | In Stock | |
10 mg | $208 | In Stock | |
25 mg | $415 | In Stock | |
50 mg | $665 | In Stock |
Description | Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer. |
In vitro | The limitations of currently available antifungal agents and the rapid emergence of drug-resistant strains necessitate more efficient approaches to screening and developing novel antifungal drugs. METHODS AND RESULTS: The antifungal activity of the natural products of a series of plants was evaluated and Wighteone, 5, 7, 4'-trihydroxy-6-(gamma,gamma-dimethylallyl)isoflavone showed excellent anti-yeast activity (MIC against Saccharomyces cerevisiae was 4 microg/ml). METHODS AND RESULTS: Transcriptome profiling of Wighteone-treated S. cerevisiae indicated that Wighteone is different from commonly used antifungal compounds in its mode of action. |
Alias | Erythrinin B, 6-Isopentenylgenistein |
Molecular Weight | 338.35 |
Formula | C20H18O5 |
Cas No. | 51225-30-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (236.44 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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