Shopping Cart

Remove All

Your shopping cart is currently empty

Xanomeline tartrate

Resource Download

Xanomeline tartrate

Catalog No. T39010Cas No. 152854-19-8

Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$64	In Stock
25 mg	$98	In Stock
50 mg	$148	In Stock
100 mg	$217	In Stock

Bulk & Custom

Add to Cart

Questions

Product Introduction

Bioactivity

Description	Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.
In vitro	Xanomeline tartrate (LY 246708) (0.1-10 μM; CNS4U) shows an overall increase in average firing rate, indicating the functional presence of M1 receptors in hiPSC-derived neurons[1].
In vivo	In Male Cebus apella monkeys, Xanomeline tartrate ( 0.5-3 mg / kg ; s.c. ; 1-3 hours ) can induce salivation and vomiting in some monkeys[3].
Alias	LY246708 tartrate, LY-246708 tartrate, LY 246708 tartrate

Chemical Properties

Molecular Weight	431.5
Formula	C18H29N3O7S
Cas No.	152854-19-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 200 mg/mL (463.50 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3175 mL	11.5875 mL	23.1750 mL	115.8749 mL
5 mM	0.4635 mL	2.3175 mL	4.6350 mL	23.1750 mL
10 mM	0.2317 mL	1.1587 mL	2.3175 mL	11.5875 mL
20 mM	0.1159 mL	0.5794 mL	1.1587 mL	5.7937 mL
50 mM	0.0463 mL	0.2317 mL	0.4635 mL	2.3175 mL
100 mM	0.0232 mL	0.1159 mL	0.2317 mL	1.1587 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc