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Zoniporide
Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases.
Catalog No. T21996LCas No. 241800-98-6
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Zoniporide
Catalog No. T21996LAlias CP-597396, CP597396, CP 597396Cas No. 241800-98-6
Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases. |
| In vivo | In rats, Zoniporide (1 mg/kg; i.v.) shows the AUC0-∞ = 0.07 μg h/mL, and t1/2 are 0.5 hours, respectively. [1] In open chest anesthetized rabbits, Zoniporide (0.25, 1, 4 mg/kg; i.v.) dose-dependently reduces infarct size with an ED50 = 0.45 mg/kg/h. Zoniporide exhibits moderate plasma protein binding with t1/2 of 1.5h in monkeys. [2] |
| Alias | CP-597396, CP597396, CP 597396 |
| Molecular Weight | 320.35 |
| Formula | C17H16N6O |
| Cas No. | 241800-98-6 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL(312.16 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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