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Zoniporide
🥰Excellent
Catalog No. T21996LCas No. 241800-98-6
Alias CP-597396, CP597396, CP 597396
Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases.
Zoniporide
🥰Excellent
Catalog No. T21996LAlias CP-597396, CP597396, CP 597396Cas No. 241800-98-6
Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 185 € | In Stock | |
| 5 mg | 458 € | In Stock | |
| 10 mg | 657 € | In Stock | |
| 25 mg | 1.026 € | In Stock | |
| 50 mg | 1.415 € | In Stock | |
| 100 mg | 1.871 € | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases. |
| In vivo | In rats, Zoniporide (1 mg/kg; i.v.) shows the AUC0-∞ = 0.07 μg h/mL, and t1/2 are 0.5 hours, respectively. [1] In open chest anesthetized rabbits, Zoniporide (0.25, 1, 4 mg/kg; i.v.) dose-dependently reduces infarct size with an ED50 = 0.45 mg/kg/h. Zoniporide exhibits moderate plasma protein binding with t1/2 of 1.5h in monkeys. [2] |
| Alias | CP-597396, CP597396, CP 597396 |
| Molecular Weight | 320.35 |
| Formula | C17H16N6O |
| Cas No. | 241800-98-6 |
| Smiles | O=C(NC(=N)N)C=1C=NN(C2=CC=CC3=NC=CC=C32)C1C4CC4 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL(312.16 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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