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(±)-Cannabichromene

Catalog No. TN3575   CAS 20675-51-8
Synonyms: Cannabichromene, Cannabichrome

(±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1.

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(±)-Cannabichromene Chemical Structure
(±)-Cannabichromene, CAS 20675-51-8
Pack Size Availability Price/USD Quantity
1 mg In stock $ 173.00
5 mg In stock $ 432.00
10 mg In stock $ 628.00
25 mg In stock $ 986.00
50 mg In stock $ 1,320.00
100 mg In stock $ 1,790.00
500 mg In stock $ 3,590.00
1 mL * 10 mM (in DMSO) In stock $ 550.00
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Purity: 99.1%
Purity: 96.89%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description (±)-Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1.
In vitro Cannabichromene (CBC)? activated CB2 but not CB1 receptors to produce hyperpolarization of AtT20 cells.?This activation was inhibited by a CB2 receptor antagonist AM630, and sensitive to Pertussis toxin.?Application of CBC reduced activation of CB2 , but not CB1 , receptors by subsequent co-application of CP55,940, an efficacious CB1 and CB2 receptor agonist.?Continuous CBC application induced loss of cell surface CB2 receptors and desensitization of the CB2 receptor-induced hyperpolarization[2].
Source
Synonyms Cannabichromene, Cannabichrome
Molecular Weight 314.46
Formula C21H30O2
CAS No. 20675-51-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/ml (174.88 mM)

TargetMolReferences and Literature

1. The effect of cannabichromene on adult neural stem/progenitor cells. Neurochem Int. 2013 Nov;63(5):432-7. 2. Udoh M P , Santiago M J , Mcgregor I S , et al. Cannabichromene is a cannabinoid CB2 receptor agonist. 2018.

Related compound libraries

This product is contained In the following compound libraries:
GPCR Compound Library Anti-Cancer Active Compound Library Anti-Tumor Natural Product Library Bioactive Compound Library Traditional Chinese Medicine Monomer Library NO PAINS Compound Library Preclinical Compound Library Anti-Cancer Compound Library Chinese Pharmacopoeia Natural Product Library Anti-Inflammatory Traditional Chinese Medicine Compound Library

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Keywords

(±)-Cannabichromene 20675-51-8 GPCR/G Protein Cannabinoid Receptor Inhibitor (±)Cannabichromene Cannabichromene (±) Cannabichromene DL-cannabichromene Cannabichrome inhibit inhibitor

 

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