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(1R,2S)-VU0155041

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Purity:99.73%

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COA HPLC HNMR

(1R,2S)-VU0155041

Catalog No. T13424Cas No. 1263273-14-8

(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.

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Pack Size	Price	Availability
5 mg	$32	In Stock
10 mg	Inquiry	In Stock
25 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$31	In Stock

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Product Introduction

Bioactivity

Description	(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.
In vitro	(1R,2S)-VU0155041 is similar in potency with VU0155041 At both human and rat receptors (798 nM at human mGluR4 and 693 nM at rat mGluR4). (1R,2S)-VU0155041 (30 μM) induces concentration-dependent shifts in the baseline when examined in fold shift experiments using the thallium flux assay[1].

Chemical Properties

Molecular Weight	316.18
Formula	C14H15Cl2NO3
Cas No.	1263273-14-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 54mg/mL (170.8mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1628 mL	15.8138 mL	31.6276 mL	158.1378 mL
5 mM	0.6326 mL	3.1628 mL	6.3255 mL	31.6276 mL
10 mM	0.3163 mL	1.5814 mL	3.1628 mL	15.8138 mL
20 mM	0.1581 mL	0.7907 mL	1.5814 mL	7.9069 mL
50 mM	0.0633 mL	0.3163 mL	0.6326 mL	3.1628 mL
100 mM	0.0316 mL	0.1581 mL	0.3163 mL	1.5814 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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