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(E)-10-Hydroxynortriptyline

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Catalog No. T38131Cas No. 47132-16-1
Alias E-10-OH-NT

(E)-10-Hydroxynortriptyline (E-10-OH-NT) is an active metabolite of Nortriptyline with anxiolytic activity and affinity for muscarinic acetylcholine receptors, which can be used in the study of neurological disorders.

(E)-10-Hydroxynortriptyline

(E)-10-Hydroxynortriptyline

🥰Excellent
Catalog No. T38131Alias E-10-OH-NTCas No. 47132-16-1
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is an active metabolite of Nortriptyline with anxiolytic activity and affinity for muscarinic acetylcholine receptors, which can be used in the study of neurological disorders.
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1 mg$157In Stock
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Product Introduction

Bioactivity
Description
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is an active metabolite of Nortriptyline with anxiolytic activity and affinity for muscarinic acetylcholine receptors, which can be used in the study of neurological disorders.
AliasE-10-OH-NT
Chemical Properties
Molecular Weight279.38
FormulaC19H21NO
Cas No.47132-16-1
SmilesC(\CCNC)=C\1/C=2C(C(O)CC=3C1=CC=CC3)=CC=CC2
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 1.00 mg/mL (3.58 mM), Sonication is recommended
Methanol: 20.00 mg/mL (71.59 mM), Sonication is recommended
Solution Preparation Table
H2O/Methanol
1mg5mg10mg50mg
1 mM3.5794 mL17.8968 mL35.7935 mL178.9677 mL
Methanol
1mg5mg10mg50mg
5 mM0.7159 mL3.5794 mL7.1587 mL35.7935 mL
10 mM0.3579 mL1.7897 mL3.5794 mL17.8968 mL
20 mM0.1790 mL0.8948 mL1.7897 mL8.9484 mL
50 mM0.0716 mL0.3579 mL0.7159 mL3.5794 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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