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(S)-3,4-DCPG HCl
🥰Excellent
Catalog No. T23288L
Alias (S)-3,4-Dicarboxyphenylglycine HCl, (S)-3,4-DCPG HCl(201730-11-2 Free base)
(S)-3,4-DCPG HCl ((S)-3,4-Dicarboxyphenylglycine HCl) is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expressing AV12-664 cells with an EC50 of 31 nM.
(S)-3,4-DCPG HCl
🥰Excellent
Purity: 99.90%
Catalog No. T23288LAlias (S)-3,4-Dicarboxyphenylglycine HCl, (S)-3,4-DCPG HCl(201730-11-2 Free base)
(S)-3,4-DCPG HCl ((S)-3,4-Dicarboxyphenylglycine HCl) is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expressing AV12-664 cells with an EC50 of 31 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $193 | In Stock | |
| 5 mg | $486 | In Stock | |
| 10 mg | $695 | In Stock | |
| 25 mg | $1,090 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock | |
| 500 mg | $3,960 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $437 | In Stock |
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Purity:99.90%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (S)-3,4-DCPG HCl ((S)-3,4-Dicarboxyphenylglycine HCl) is a selective metabotropic glutamate receptor 8a (mGluR8a) agonist that has an effect on human mGluR8-expressing AV12-664 cells with an EC50 of 31 nM. |
| Targets&IC50 | mGluR8a (human):31 nM (EC50) |
| In vivo | (S)-3,4-DCPG (3-100 mg/kg, i.p.) maked c-Fos as an indicator of neuronal activity in specific brain regions 2 hours after systemic administration. In wild-type mice, (S)-3,4-DCPG (100 mg/kg) significantly increased c-Fos expression in several stress-related brain regions: paraventricular nucleus of the hypothalamus, central nucleus of the amygdala, lateral parabrachial nucleus and locus coeruleus.[2] |
| Alias | (S)-3,4-Dicarboxyphenylglycine HCl, (S)-3,4-DCPG HCl(201730-11-2 Free base) |
| Molecular Weight | 275.64 |
| Formula | C10H10ClNO6 |
| Smiles | OC(C1=C(C=CC([C@H](N)C(O)=O)=C1)C(O)=O)=O.[H]Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (36.28 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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