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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $30 | In Stock | |
5 mg | $50 | In Stock | |
10 mg | $76 | In Stock | |
25 mg | $122 | In Stock | |
50 mg | $173 | In Stock | |
100 mg | $235 | In Stock |
Description | (S,R,S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to create PROTACs (e.g., GMB-475), which effectively induce the degradation of BCR-ABL1, demonstrated by an IC50 of 1.11 μM in Ba/F3 cells. |
Alias | VH032-NH2 TFA, VHL ligand 1 TFA |
Molecular Weight | 544.59 |
Formula | C24H31F3N4O5S |
Cas No. | 1631137-51-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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