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(S,S,S)-AHPC hydrochloride

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Catalog No. T13877Cas No. 2115897-23-7
Alias (S,S,S)-VH032-NH2 hydrochloride

(S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) is a VHL amino building block and ligand used as a negative control for (S,R,S)-AHPC. It is based on VH032 and is employed in the recruitment of the VHL protein.

(S,S,S)-AHPC hydrochloride

(S,S,S)-AHPC hydrochloride

🥰Excellent
Purity: 98.22%
Catalog No. T13877Alias (S,S,S)-VH032-NH2 hydrochlorideCas No. 2115897-23-7
(S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) is a VHL amino building block and ligand used as a negative control for (S,R,S)-AHPC. It is based on VH032 and is employed in the recruitment of the VHL protein.
Pack SizePriceAvailabilityQuantity
10 mg$38In Stock
25 mg$65In Stock
50 mg$98In Stock
100 mg$158In Stock
1 mL x 10 mM (in DMSO)$38In Stock
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Purity:98.22%
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Product Introduction

Bioactivity
Description
(S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) is a VHL amino building block and ligand used as a negative control for (S,R,S)-AHPC. It is based on VH032 and is employed in the recruitment of the VHL protein.
In vitro
VHL is one of the most popular E3 ligases being recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein.
Alias(S,S,S)-VH032-NH2 hydrochloride
Chemical Properties
Molecular Weight467.02
FormulaC22H31ClN4O3S
Cas No.2115897-23-7
SmilesCl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)cc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 99 mg/mL (211.98 mM), Sonication is recommended.
DMSO: 60 mg/mL (128.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.1412 mL10.7062 mL21.4124 mL107.0618 mL
5 mM0.4282 mL2.1412 mL4.2825 mL21.4124 mL
10 mM0.2141 mL1.0706 mL2.1412 mL10.7062 mL
20 mM0.1071 mL0.5353 mL1.0706 mL5.3531 mL
50 mM0.0428 mL0.2141 mL0.4282 mL2.1412 mL
100 mM0.0214 mL0.1071 mL0.2141 mL1.0706 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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