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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $37 | In Stock | |
5 mg | $57 | In Stock | |
10 mg | $89 | In Stock | |
25 mg | $153 | In Stock | |
50 mg | $197 | In Stock | |
100 mg | $289 | In Stock |
Description | (S, R, S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) is a synthesized E3 ligase ligand-linker conjugate. (S, R, S)-AHPC-PEG3-N3 incorporates the (S, R, S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. |
In vitro | (S,R,S)-AHPC-PEG3-N3 is extracted from patent WO/2016/146985A1, figure 11. PROTAC has been developed with an A-L-B structure that can tether a bromodomain inhibitor via a moiety which binds to a protein within the bromo- and Extra-terminal (BET) family of proteins to a small molecule E3 ubiquintin ligase protein binding ligand compound via a suitable linker[1][2]. |
Alias | VHL Ligand-Linker Conjugates 8, VH032-PEG3-N3, E3 ligase Ligand-Linker Conjugates 12 |
Molecular Weight | 645.77 |
Formula | C30H43N7O7S |
Cas No. | 1797406-80-4 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (77.43 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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