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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

1,3,6-Tri-O-galloyl-beta-D-glucose

🥰Excellent
Catalog No. TN1166Cas No. 18483-17-5
Alias 1,3,6-Tri-O-galloyl-β-D-glucose, 1,3,6-Tri-O-galloylglucose

1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound found in Black Walnut Kernels, exhibiting anti-inflammatory activity.

1,3,6-Tri-O-galloyl-beta-D-glucose

1,3,6-Tri-O-galloyl-beta-D-glucose

🥰Excellent
Purity: 99.37%
Catalog No. TN1166Alias 1,3,6-Tri-O-galloyl-β-D-glucose, 1,3,6-Tri-O-galloylglucoseCas No. 18483-17-5
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound found in Black Walnut Kernels, exhibiting anti-inflammatory activity.
Pack SizePriceAvailabilityQuantity
1 mg112 €In Stock
5 mg276 €In Stock
10 mg410 €In Stock
25 mg680 €In Stock
50 mg937 €In Stock
1 mL x 10 mM (in DMSO)558 €In Stock
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Purity:99.37%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound found in Black Walnut Kernels, exhibiting anti-inflammatory activity.
In vitro
The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively.
Alias1,3,6-Tri-O-galloyl-β-D-glucose, 1,3,6-Tri-O-galloylglucose
Chemical Properties
Molecular Weight636.47
FormulaC27H24O18
Cas No.18483-17-5
SmilesO[C@@H]1[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](O)[C@H]1OC(=O)c1cc(O)c(O)c(O)c1
Relative Density.1.98 g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

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