Shopping Cart
- Remove All
Your shopping cart is currently empty
Dimethylaminomicheliolide HCl
Catalog No. T60102LCas No. 1403357-80-1
Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate kinase 2 (PKM2) and reconnecting aerobic cell populations.
Dimethylaminomicheliolide HCl
Catalog No. T60102LCas No. 1403357-80-1
Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate kinase 2 (PKM2) and reconnecting aerobic cell populations.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $483 | In Stock | |
| 10 mg | $692 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,970 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Dimethylaminomicheliolide HCl"
DL-Serine
T8363302-84-1
DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.
- $48
Size
QTY
Disodium monofluorophosphate
Sodium Monofluorophosphate, NSC248
T074510163-15-2
Disodium monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase.
- $29
Size
QTY
TEPP-46
Cited
ML265
T72141221186-53-3
TEPP-46 (ML265) is an activator of pyruvate kinase M2 (PKM2) (AC50=92 nM), selective for PKM1, PKL and PKR. TEPP-46 has antitumor activity.
- $41
Size
QTY
CitedPKM2-IN-1 Cited
PKM2 inhibitor, compound 3k
T417094164-88-2
PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 μM, while the IC50 for PKM1 is 4-5 times higher.
- $34
Size
QTY
CitedMitapivat
PKR-IN-1
T42231260075-17-9
Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.
- $34
Size
QTY
PKM2 activator 2
T627581186660-06-9
PKM2 activator 2, with an AC50 value of 66 nM, is a pyruvate kinase M2 (PKM2) activator that demonstrates anti-tumor proliferative properties and attenuates the Warburg effect by normalizing cellular glycolytic metabolism through the activation of PKM2.
- $52
Size
QTY
DASA-58 Cited
T68161203494-49-8
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
- $37
Size
QTY
CitedPKM2 inhibitor G
T67900904457-46-1
PKM2 inhibitor G is a inhibitor of pyruvate kinase.
- $195
Size
QTY
Shikonin
Cited
NSC 252844, Isoarnebin 4, C.I. 75535, Anchusa acid, Alkanna Red, (+)-Shikonin
T1125517-89-5
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
- $29
Size
QTY
CitedPKM2 activator 5
T72693796092-26-7
PKM2 activator 5 is a novel and potent PKM2 activator (AC50: 0.316 µM) with potential anticancer activity for the study of cancer metabolism-related diseases.
- $47
Size
QTY
Select Batch
Purity:99.55%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate kinase 2 (PKM2) and reconnecting aerobic cell populations. |
| Molecular Weight | 329.86 |
| Formula | C17H28ClNO3 |
| Cas No. | 1403357-80-1 |
Storage & Solubility Information
| Storage | store at low temperature | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (151.58 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Dimethylaminomicheliolide HCl | purchase Dimethylaminomicheliolide HCl | Dimethylaminomicheliolide HCl cost | order Dimethylaminomicheliolide HCl | Dimethylaminomicheliolide HCl chemical structure | Dimethylaminomicheliolide HCl formula | Dimethylaminomicheliolide HCl molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.