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2-Hydroxy atorvastatin calcium salt

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Catalog No. TQ0045Cas No. 265989-46-6

2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of atorvastatin calcium salt, a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).

2-Hydroxy atorvastatin calcium salt

2-Hydroxy atorvastatin calcium salt

😃Good
Purity: 97.06%
Catalog No. TQ0045Cas No. 265989-46-6
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of atorvastatin calcium salt, a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).
Pack SizePriceAvailabilityQuantity
1 mg$182 In Stock
5 mg$389 6-8 weeks
50 mgInquiry6-8 weeks
1 mL x 10 mM (in DMSO)$845 6-8 weeks
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Purity:97.06%
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Product Introduction

Bioactivity
Description
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of atorvastatin calcium salt, a potent HMG-CoA reductase inhibitor (IC50 = 8 nM).
Chemical Properties
Molecular Weight1187.341
FormulaC66H68CaF2N4O12
Cas No.265989-46-6
Smiles[Ca++].CC(C)c1c(C(=O)Nc2ccccc2O)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1.CC(C)c1c(C(=O)Nc2ccccc2O)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (16.82 mM), when pH is adjusted to 3 with HCl. Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8422 mL4.2111 mL8.4222 mL42.1109 mL
5 mM0.1684 mL0.8422 mL1.6844 mL8.4222 mL
10 mM0.0842 mL0.4211 mL0.8422 mL4.2111 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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