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2-Hydroxyisobutyric acid

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Catalog No. T4787Cas No. 594-61-6
Alias α-Hydroxyisobutyric acid

2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainly through expired air as the unchanged compound. MTBE is to some extent metabolised to t-butyl alcohol (TBA) and formaldehyde and oxidised to 2-methyl-1,2-propanediol and a-hydroxy isobuturic acid. 2-Hydroxyisobutyric acid has been used as an arial bactericide.

2-Hydroxyisobutyric acid

2-Hydroxyisobutyric acid

🥰Excellent
Purity: 99.05%
Catalog No. T4787Alias α-Hydroxyisobutyric acidCas No. 594-61-6
2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainly through expired air as the unchanged compound. MTBE is to some extent metabolised to t-butyl alcohol (TBA) and formaldehyde and oxidised to 2-methyl-1,2-propanediol and a-hydroxy isobuturic acid. 2-Hydroxyisobutyric acid has been used as an arial bactericide.
Pack SizePriceAvailabilityQuantity
200 mg$33In Stock
500 mg$55In Stock
1 g$79In Stock
5 g$193In Stock
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Purity:99.05%
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Product Introduction

Bioactivity
Description
2-Hydroxyisobutyric acid (α-Hydroxyisobutyric acid) is a metabolite of methyl tert-butyl ether (MTBE). MTBE may be obtained through environmental exposure. MTBE is rapidly eliminated from the body, mainly through expired air as the unchanged compound. MTBE is to some extent metabolised to t-butyl alcohol (TBA) and formaldehyde and oxidised to 2-methyl-1,2-propanediol and a-hydroxy isobuturic acid. 2-Hydroxyisobutyric acid has been used as an arial bactericide.
In vivo
Glycerol can induce acute renal failure in rat models. Acute renal failure induced by glycerol or uranyl nitrate reduces the hepato-biliary transport of some drugs, modulates the distribution of drugs into the central nervous system and affects the activity of various hepatic microsomal enzymes.
Aliasα-Hydroxyisobutyric acid
Chemical Properties
Molecular Weight104.1
FormulaC4H8O3
Cas No.594-61-6
SmilesCC(C)(O)C(O)=O
Relative Density.11412 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (480.31 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM9.6061 mL48.0307 mL96.0615 mL480.3074 mL
5 mM1.9212 mL9.6061 mL19.2123 mL96.0615 mL
10 mM0.9606 mL4.8031 mL9.6061 mL48.0307 mL
20 mM0.4803 mL2.4015 mL4.8031 mL24.0154 mL
50 mM0.1921 mL0.9606 mL1.9212 mL9.6061 mL
100 mM0.0961 mL0.4803 mL0.9606 mL4.8031 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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